Using Python to solve problems in bioinformatics

Linear splines

The use of linear splines to reduce the effect of noise in time-course gene expression data is described in our paper "Statistical analysis of a small set of time-ordered gene expression data using linear splines" ( Bioinformatics, 18: 1477--1485 (2002). For the linear spline fitting procedure, we wrote a C extension module to Python. This extension module is available in source form or as a Windows installer for Python 2.2 or Python 2.3. This software package (with patent pending) is free of charge for academic use only.




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