Using Python to solve problems in bioinformatics
The use of linear splines to reduce the effect of noise in time-course gene expression data is described in our paper "Statistical analysis of a small set of time-ordered gene expression data using linear splines" (
Bioinformatics, 18: 1477--1485 (2002).
For the linear spline fitting procedure, we wrote a C extension module to Python.
This extension module is available in source form or as a Windows installer for Python 2.2 or Python 2.3.
This software package (with
patent pending) is free of charge for academic use only.
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